Publications

Burnier J.V., Wang N., Michel R.P., Hassanain M., Li S., Lu Y., Metrakos P., Antecka E., Burnier M.N., Ponton A., Gallinger S., and Brodt P. Type IV collagen-initiated signals provide survival and growth cues required for liver metastasis. Oncogene 30:
Wu Y., Brodt P., Sun H., Mejia W., Novosyadlyy R., Mendoza A., Hong S-H., Khanna C., and Yakar S. IGF-1 regulates the liver microenvironment in obese mice and promotes liver metastasis. Cancer Research 70:57-67, 2010
Li S., Zhang D., Yang L., Wang N., Lin R., and Brodt P. Transcriptional regulation of PKC-α by the IGF-I receptor alters the matrix metalloproteinase profile of tumor cells. Mol. Endocrinology 23(12):2013-25, 2009
Wang N., Fallavollita L., Nguyen L., Burnier J., Rafei M., Galipeau J. Yakar S., and Brodt P. Autologous bone marrow derived mesenchymal stromal cells genetically engineered to express an IGF-I receptor decoy prevent the growth of liver metastases. Mo
Samani AA, Yakar S., LeRoith D. and Brodt P. The role of the IGF system in cancer: overview and recent insights – Endocrine Rev. 28:20-47, 2007
Auguste P., Fallavollita L., Wang N., Bikfalvi A., and Brodt P. The host pro-inflammatory response promotes liver metastasis by increasing tumor cell arrest and extravasation. Am. J. Pathol. 170:1781-1792, 2007
Samani AA, Yakar S., LeRoith D. and Brodt P. The role of the IGF system in cancer: overview and recent insights – Endocrine Rev. 28:20-47, 2007
Wang N., Thuraisingam T., Ding A., Radzioch D. and Brodt P. The secretory leukocyte protease inhibitor is an IGF regulated protein that protects against liver metastasis by attenuating the host pro-inflammatory response. Cancer Research 66:3062-3070, 200
Khatib, A.-M., August P., Fallavollita, L., Wang N., Samani A., Kontogiannea M, Meterissian S. and Brodt P. Characterization of the host pro-inflammatory response to tumor cells during the initial stages of liver metastasis. Am. J. Pathol. 167:749-59,
Samani A., Chevet E., Fallavollita L., Brodt P., Loss of tumorigenicity and metastatic potential in carcinoma cells expressing the extracellular domain of the type 1 insulin-like growth factor receptor. Cancer Research 64:3380-5, 2004

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